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⤑ About Pan3DP Data ⤑ Current Data
 

Pan3DP Data

About Our Data

The Pan3DP consortium aims to make their sequencing and imaging data open access and freely available to the science community and the general public

 
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Knowledge and innovation leading to growth are central to the Europe 2020 strategy for a smart, sustainable and inclusive economy [1]. The concept of growth or improvements through knowledge and innovation is also fundamental to modern research. However, in order for knowledge to be useful and impactful in the science community it must be shared. There are numerous positive effects of allowing wider access to scientific research. Firstly, it allows other researchers to build on previous work leading to improvements in the quality of results. It also improves efficiency by encouraging collaboration between researchers thus avoiding duplication of their efforts. Additionally, innovation is expedited resulting in progress being made sooner.

Finally, by allowing the general public access to scientific knowledge the transparency of the scientific process is improved. In order to maximize its contribution to the advancement of research, particularly in the fields of diabetes, developmental biology and regenerative medicine, the Pan3DP consortium are committed to making RNA-sequencing and imaging data generated during the project openly accessible. Together with traditional methods of academic dissemination of research such as presenting our work at scientific conferences and publishing in scientific journals, the Pan3DP consortium will also make research data freely available by adding it to relevant online data repositories.

PUBLICATIONS

  • ‘Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner.’ Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM. Dev Cell. 2024 Jan 13:S1534-5807(23)00691-3. doi: 10.1016/j.devcel.2023.12.011. Epub ahead of print. PMID: 38237591. [PubMed]

  • ‘In-Depth Analysis of the Pancreatic Extracellular Matrix during Development for Next-Generation Tissue Engineering.’ Glorieux L, Vandooren L, Derclaye S, Pyr Dit Ruys S, Oncina-Gil P, Salowka A, Herinckx G, Aajja E, Lemoine P, Spourquet C, Lefort H, Henriet P, Tyteca D, Spagnoli FM, Alsteens D, Vertommen D, Pierreux CE. Int J Mol Sci. 2023 Jun 17;24(12):10268. doi: 10.3390/ijms241210268. PMID: 37373416; PMCID: PMC10299253. [PubMed]

  • ‘3D model of mouse embryonic pancreas and endocrine compartment using stem cell-derived mesoderm and pancreatic progenitors.’ Shlomit Edri, Vardit Rosenthal, Or Ginsburg, Abigail Newman Frisch, Christophe E. Pierreux, Nadav Sharon, Shulamit Levenberg bioRxiv 2022.10.11.511696; doi: https://doi.org/10.1101/2022.10.11.511696

  • ‘Pancreatic pericytes originate from the embryonic pancreatic mesenchyme.’ Neta Harari, Lina Sakhneny, Laura Khalifa-Malka, Anke Busch, Klemens J. Hertel, Matthias Hebrok, Limor Landsman; Developmental Biology; doi: 10.1016/j.ydbio.2019.01.020; PMID: 30771302 [PubMed]

  • ‘A Specialized Niche in the Pancreatic Microenvironment Promotes Endocrine Differentiation.’ Corinna Cozzitorto, Laura Mueller, Silvia Ruzittu, Nancy Mah, David Willnow, Jean-Francois Darrigrand, Heather Wilson, Daniel Khosravinia, Amir-Ala Mahmoud, Maurizio Risolino, Licia Selleri, Francesca M. Spagnoli; Developmental Cell; doi: 10.1016/j.devcel.2020.08.003; PMID: 32857951 [PubMed]

  • ‘The Role of Vascular Cells in Pancreatic Beta-Cell Function.’ Guzel Burganova, Claire Bridges, Peter Thorn, Limor Landsman; Frontiers in Endocrinology; doi: 10.3389/fendo.2021.667170

  • ‘Beta cell dysfunction in diabetes: the islet microenvironment as an unusual suspect.’ Joana Almaça, Alejandro Caicedo, Limor Landsman; Diabetologia; doi: 10.1007/s00125-020-05186-5; PMC7655222

  • ‘Quantitative lineage analysis identifies a long-term progenitor niche for the hepato-pancreato-biliary organ system.’ David Willnow, Uwe Benary, Anca Margineanu, Maria Lillina Vignola, Igor M. Pongrac, Zahra Karimaddini, Alessandra Vigilante, Jana Wolf, Francesca M. Spagnoli; bioRxiv; doi: 10.1101/2020.08.06.240176 / Nature; doi: 10.1038/s41586-021-03844-1

  • ‘Development of a 3D atlas of the embryonic pancreas for topological and quantitative analysis of heterologous cell interactions.’ Laura Glorieux, Aleksandra Sapala, David Willnow, Manon Moulis, Shlomit Edri, Jean-Francois Darrigrand, Anat Schonblum, Lina Sakhneny, Laura Schaumann, Harold F Gomez, Christine Lang, Lisa Conrad, Fabien Guillemot, Shulamit Levenberg, Limor Landsman, Dagmar Iber, Christophe Pierreux, Francesca M Spagnoli; bioRxiv; doi: 10.1101/2021.04.28.441857 /Development, 149 (3); doi: 10.1242/dev.199655 [Development Journal PDF]

  • ‘Cell-based simulations of Notch-dependent cell differentiation on growing domains.’ Stopka Anna, Boareto do Amaral Marcelo, Iber Dagmar; bioRxiv; doi: 10.1101/859363

  • ‘Single cell transcriptomic comparison between mouse embryonic pancreas and pancreatic organoids generated from mouse embryonic stem cell-derived mesoderm and pancreatic progenitors.’ Shlomit Edri, Vardit Rosenthal, Or Ginsburg, Abigail Newman Frisch, Christophe E. Pierreux, Nadav Sharon, Shulamit Levenberg; bioRxiv; doi: 10.1101/2022.10.11.511696

  • ‘Pancreatic cell fate specification: insights into developmental mechanisms and their application for lineage reprogramming.’ Abigail Isaacson, Francesca M. Spagnoli; Current Opinion in Genetics & Development; doi: 10.1016/j.gde.2021.05.003

  • ‘Identification and implication of tissue-enriched ligands in epithelial–endothelial crosstalk during pancreas development.’ Manon Moulis, Steve Vincent, Maurice Runser, Laura Glorieux, Nicolas Dauguet, Christophe Vanderaa, Laurent Gatto, Donatienne Tyteca, Patrick Henriet, Francesca M. Spagnoli, Dagmar Iber, Christophe E. Pierreux; Scientific Reports, 12; doi: 10.1101/2022.04.19.488467